"Rx Diethylcarbamazine
Found in tropics and subtropics.
Humans serve as definitive host
Mosquitoes are intermediate hosts
LIFE CYCLE
Adult female worms produce larvae.
Larvae ingested by mosquitoes - arthropod vector.
Mosqitoes transfer larvae to humans.
Larvae move through the lymphatic system to lymph nodes in the legs and genital area.
Larvae reach sexual maturity in the afferent lymphatic vessels.
Adult female worm produces microfilariae that migrate into bloodstream.
Mosquito vector bites infected human host
ingests the microfilariae
and repeats life cycle.
Chyluria due to microfilaria in blood was discovered by Dr. Wucherer of Bahia .
Joseph Bancroft
a Brisbane physician
discovered the adult worm later to be named Wucheria bancrofti.
Features:
� Fever and painful lymphadenopathy in the groin and axillae.
� Each episode of ADL enhances the development of lymphoedema."