Von Willebrand disease

external

• Synonyms

  • Von Willebrand factor deficiency
  • vWF deficiency
  • vWD

• Causes

  • VWF gene mutation
  • Heyde syndrome

• Effects

  • Congenital coagulation defect
  • Reduced ristocetin cofactor activity
  • Prolonged activated partial thromboplastin time

• Parents

  • Autosomal dominant disorder
  • Congenital haematological disorder

• Treatments

  • Desmopressin

• Description

  • "Von Willebrand factor deficiency Factor stored in Weibel-Palade bodies. Required for platelet adhesion. Rx DDAVP"