Ulcerative colitis

external

• Synonyms

  • UC

• Causes

  • Emotional stress
  • HLA-B5
  • Irradiation

• Effects

  • Mucus in stool
  • Tenesmus
  • Dehydration
  • Toxic megacolon
  • Pseudopolyposis coli
  • Colorectal carcinoma
  • Colonic stricture
  • Primary sclerosing cholangitis
  • Multiple sclerosis
  • Chronic active hepatitis
  • Basophilia
  • Lower gastrointestinal bleed

• Parents

  • Inflammatory bowel disease

• Treatments

  • Prednisolone
  • Sulphasalazine
  • Mesalazine
  • Enema
  • Cyclosporin
  • Tacrolimus
  • Infliximab
  • Total parenteral nutrition
  • Antimuscarinic drug

• Description

  • "Mucosa and submucosa inflammation continuous from rectum proximally Ca bowel in 5% PSC in 2% Sulphasalazine reduces 1 year relapse rate from 80% to 20% commonest cause of death = toxic megacolon. "