Schizophrenia

external

• Causes

  • HLA-A28
  • Polygenic inheritance

• Effects

  • Schneider first rank criterion
  • Psychosis
  • Flat affect
  • Catatonia
  • Stupor
  • Depression
  • Apathy

• Parents

  • Psychiatric disease

• Treatments

  • Neuroleptic drug

• Description

  • "Aetiology: genetic (MZ/DZ = 4)
  • dopamine hypothesis
  • schizophrenogenic mother 1:100
  • mean age of onset 18 in men
  • 25 in women"