Renal cell carcinoma

external

• Synonyms

  • RCC
  • Renal adenocarcinoma
  • Hypernephroma

• Causes

  • Von Hippel-Lindau disease
  • Acquired renal cystic disease
  • Cigarette smoking
  • Obesity
  • Phenacetin
  • Cadmium
  • Membranous glomerulonephritis

• Effects

  • Haematuria
  • Abdominal mass
  • Chronic abdominal pain
  • Hypercalcaemia
  • Inappropriately raised erythropoietin
  • Renal vein thrombosis
  • Varicocele
  • Lung metastasis
  • Bone metastasis
  • Sterile pyuria
  • Secondary amyloidosis
  • Dermatomyositis
  • Ectopic parathyroid hormone secretion
  • Cancers with polygenic inheritance
  • Hypernephroma triad
  • Increased vascular tone

• Parents

  • Kidney carcinoma

• Children

  • Chromophobe renal cell carcinoma

• Treatments

  • Radical nephrectomy
  • Embolisation
  • Growth factor inhibitor
  • Bevacizumab
  • Sunitnib
  • Cytotoxic drug

• Description

  • "STAGING: T1 < 7 cm Limited to kidney T2 7-10 cm Limited to kidney T3 Renal vein perinephric tissues involved. T4 Distant spread "