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A frequent occurrence in the hospitalized setting
A few patients will have marked polyuria (>4-5L per day) after release of bladder outflow obstruction.
Mechanism:
1.Decreased tubular reabsorption of sodium secondary to altered expression of proximal and distal sodium transporters.
2.Inability to concentrate urine
secondary to decreased response to ADH
4.Increased production of prostaglandins immediately following relief of obstruction.
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