Polygenic inheritance

external

• Synonyms

  • Familial disorder
  • Family history

• Effects

  • Essential hypertension
  • Atherosclerosis
  • Obesity
  • Gestational diabetes
  • Pre-eclampsia
  • Cholestasis of pregnancy
  • Atopy
  • Gastric adenocarcinoma
  • Colorectal carcinoma
  • Carcinoma of pancreas
  • Carcinoma of breast
  • Prostate cancer
  • Wilm's tumour
  • Malignant melanoma
  • Hodgkin lymphoma
  • Epithelial ovarian tumour
  • Uterine fibroid
  • Ankylosing spondylitis
  • Rheumatoid arthritis
  • Osteoarthritis
  • Chronic glaucoma
  • Myopia
  • Hypermetropia
  • Acne vulgaris
  • Ichthyosis
  • Cholasma
  • Hashimoto thyroiditis
  • Congenital pyloric stenosis
  • Dupuytren's contracture
  • Schizophrenia
  • Anxiety disorder
  • Bipolar disorder
  • Autism spectrum disorder
  • Congenital malformation
  • Varicose veins of leg
  • Inflammatory bowel disease
  • Insulin resistance

• Parents

  • Genetic disease

• Description

  • "Effect of multiple genes in combination with lifestyle and environmental factors. The diseases tend to run in families
  • but the inheritance does not fit simple patterns as with Mendelian diseases. However with time
  • the genes may eventually be located. "