Paraproteinaemia

external

• Causes

  • Monoclonal gammopathy of unknown significance
  • Myeloma
  • Waldenstrom macroglobulinaemia
  • Systemic amyloidosis
  • Heavy chain disease
  • Haematological malignancy
  • Plasmacytoma
  • POEMS syndrome

• Effects

  • Raised ESR
  • Monoclonal band
  • Hyperviscosity
  • Papilloedema
  • Hypogammaglobulinaemia
  • Leukonychia