Myeloma

external

• Synonyms

  • Multiple myeloma
  • MM

• Causes

  • POEMS syndrome
  • Monoclonal gammopathy of unknown significance

• Effects

  • Bone metastasis
  • Back pain
  • Paraproteinaemia
  • Osteolysis
  • Pepper-pot skull
  • Bence Jones proteinuria
  • Hypophosphataemia
  • Osteoporosis
  • Pancytopaenia
  • Rouleaux
  • Myeloma renal disease
  • Type I cryoglobulinaemia
  • Erythema multiforme
  • Amyloid light chain
  • Insulin autoantibodies
  • Carpal tunnel syndrome
  • Sideroblastic anaemia
  • Pyoderma gangrenosum
  • Ichthyosis
  • Small fibre neuropathy
  • Cutis laxa
  • Bone pain
  • Acquired Fanconi syndrome
  • Crystalline keratopathy
  • Demyelination of peripheral nerve

• Parents

  • Haematological malignancy
  • Lymphoproliferative disorder