Metachromatic leukodystrophy

external

• Synonyms

  • MLD
  • Arylsulfatase A deficiency
  • Sulphatide sulphatase deficiency
  • Sulphatide accumulation disorder
  • Cerebroside-sulphatase deficiency
  • MCLD

• Effects

  • Demyelination of central nervous system
  • Optic atrophy
  • Mental retardation
  • Early onset dementia
  • Psychosis
  • Chronic pancreatitis
  • Global developmental delay
  • Abnormal white cell enzyme
  • Metabolic epilepsy
  • Demyelination of peripheral nerve

• Parents

  • Leukodystrophy
  • Sphingolipidosis

• Description

  • "Sulphatide accumulation in the CNS"