Liver metastasis

external

• Synonyms

  • Liver mets

• Causes

  • Gastrointestinal carcinoma
  • Ovarian tumour
  • Carcinoma of breast
  • Testicular tumour
  • Malignant melanoma
  • Intra-abdominal malignancy
  • Hepatoblastoma

• Effects

  • Abdominal mass
  • Irregular liver edge
  • Hard nodular liver
  • Abdominal arterial bruit
  • Tender hepatomegaly
  • Chronic liver disease
  • Hepatic vein compression
  • Hepatic friction rub

• Parents

  • Carcinoma of liver
  • Liver disease
  • Metastasis

• Description

  • "Liver secondaries Amenable to resection = 20% Resectable if: � Limited number of lesions. � Intrahepatic locations of lesions. � Lack of major vascular involvement. � Absent of extrahepatic disease. � Sufficient functional hepatic reserve Sloane Kettering results 2013 Resection + Hepatic Arterial Infusion Chemotherapy 5yr survival =50% 10yrs survival =30% Following resection
  • recurrence will occur in70 %. Hence the need for Arterial chemotherapy. "