Increased androgen secretion

external

• Causes

  • Adrenal cortical hyperfunction
  • 21-hydroxylase deficiency
  • Ovarian tumour
  • Adrenal adenoma
  • McCune Albright syndrome
  • Aminoglutethimide
  • Leydig cell tumour

• Effects

  • Virilisation
  • Precocious puberty
  • Polycystic ovary syndrome
  • Increased urinary dehydroepiandrosterone
  • Tall stature