Hypertrophic cardiomyopathy

external

• Synonyms

  • HOCM
  • Hypertrophic obstructive cardiomyopathy

• Causes

  • Friedrich ataxia
  • Fabry disease
  • Acromegaly
  • Sarcomeric mutation

• Effects

  • Left ventricular hypertrophy
  • Left ventricular outflow obstruction
  • Ejection systolic murmur
  • Sudden fall in blood pressure
  • Sudden death
  • Dyspnoea
  • Palpitation
  • Mitral regurgitation
  • Myxoid degeneration
  • Myocardial ischaemia
  • Systolic anterior motion of mitral valve
  • Asymmetrical septal hypertrophy
  • Sick sinus syndrome
  • Jerky sustained pulse
  • Double apex beat
  • Third heart sound
  • Fourth heart sound

• Parents

  • Cardiomyopathy
  • Autosomal dominant disorder

• Treatments

  • Amiodarone
  • Beta adrenoceptor blocker
  • Implantable defibrillator

• Description

  • "0.2% prevalence 2 per 100
  • 000 incidence 90% have family Hx Sudden cardiac death is 3% per year Rx amiodarone"