High oestrogen

external

• Causes

  • Oral contraceptive pill
  • Chronic liver disease
  • Liver failure
  • Adrenal adenoma
  • Androgen resistance

• Effects

  • Palmar erythema
  • Telangiectasia
  • Gynaecomastia
  • Testicular atrophy
  • Decreased body hair
  • Impotence
  • Gum hyperplasia
  • Acanthosis nigricans
  • Carpal tunnel syndrome
  • Carcinoma of endometrium
  • Uterine fibroid
  • Increased thyroid-binding globulin
  • Secondary hyperlipidaemia
  • High high density lipoprotein
  • Hypertriglyceridaemia
  • Acquired hypercoagulable state

• Parents

  • Sex hormone imbalance