Haemophagocytosis syndrome

external

• Causes

  • Epstein Barr virus
  • Cytomegalovirus
  • Herpes simplex virus
  • Adenovirus
  • Haematological malignancy
  • Interferon gamma
  • Tumour necrosis factor alpha
  • Interleukin-1

• Effects

  • Aplastic anaemia
  • Hepatomegaly
  • Splenomegaly

• Parents

  • Haematological autoimmune disease

• Description

  • "Activated macrophages ingest cells in marrow Rx steroids + cyclosporin"