Familial amyloidotic polyneuropathy

external

• Synonyms

  • FAPN
  • Transthyretin-related amyloidosis
  • SPTLC1 mutation
  • Familial amyloid polyneuropathy
  • TTR-related amyloidosis
  • ATTR
  • Senile systemic amyloidosis

• Effects

  • Systemic amyloidosis
  • Autonomic neuropathy
  • Large fibre neuropathy
  • Charcot joints
  • Malabsorption state
  • Lattice corneal dystrophy
  • Cutis laxa

• Parents

  • Autosomal dominant disorder