Familial adenomatous polyposis coli

external

• Synonyms

  • FPC
  • APC
  • Adenopolyposis coli
  • Familial polyposis coli
  • FAP

• Causes

  • APC gene mutation
  • Turcot syndrome

• Effects

  • Colonic polyp
  • Malignant transformation
  • Hepatoblastoma

• Parents

  • Autosomal dominant disorder
  • Congenital neoplastic syndrome

• Description

  • "Chromosome 5 Accounts for only 1% of colon Ca Invariably results in Ca by age 40"