Disseminated intravascular coagulation

external

• Synonyms

  • DIC

• Causes

  • Shock
  • Microvasculitis
  • Coagulating toxin
  • Neoplastic coagulation factors
  • Acute pancreatitis
  • Long bone fracture
  • Acute intravascular haemolysis
  • Abruptio placentae
  • Septic abortion
  • Rhesus incompatibility
  • Retained dead fetus
  • Amniotic fluid embolism
  • Toxaemia
  • Neuroleptic malignant syndrome
  • Acute promyelocytic leukaemia
  • Heatstroke
  • Hypothermia
  • Liver failure
  • Primary vasculitis
  • Kasabach-Merritt syndrome
  • Aortic aneurysm
  • Giant haemangioma
  • Soft tissue injury
  • Rhabdomyolysis

• Effects

  • Intravascular thrombus formation
  • Microangiopathic haemolytic anaemia
  • Clotting factor deficiency
  • Diffuse organ ischaemia
  • Sheehan post-partum pituitary necrosis
  • Adult respiratory distress syndrome
  • Marantic endocarditis
  • Thrombophlebitis migrans
  • Low fibrinogen
  • Acquired hypercoagulable state

• Parents

  • Haematological pathology
  • Complication of pregnancy
  • Ten serious rashes