Diabetic nephropathy

external

• Synonyms

  • Nodular glomerulosclerosis
  • Kimmelstiel-Wilson syndrome

• Causes

  • Diabetes mellitus

• Effects

  • Membranous glomerulonephritis
  • Chronic renal failure
  • Mesangial widening
  • Thickened basement membrane
  • Renal capillary obliteration
  • Diffuse glomerulosclerosis
  • Renal arteriosclerosis
  • Secondary nephrotic glomerular disease

• Description

  • "40% IDDM develop nephropathy after 40 years 25% of Type II develop nephropathy after 20 years Clinical triad of hypertension
  • proteinuria and impaired renal function Progression inevitable Rx ACEI or AT2RB"