Dermatomyositis

external

• Causes

  • Anti-Jo antibody
  • Carcinoma of breast
  • Bronchial carcinoma
  • Gynaecological cancer
  • Gastric adenocarcinoma
  • Colorectal carcinoma
  • Testicular tumour
  • Mixed connective tissue disease
  • Anti-PM/Scl antibody
  • Renal cell carcinoma

• Effects

  • Myositis
  • Cryptogenic organising pneumonia
  • Ectopic calcification
  • Intestinal pseudoobstruction
  • Gottron papules
  • Raynaud phenomenon
  • Erythema multiforme
  • Nail-fold telangiectasia
  • Migratory polyarthritis
  • Heliotrope rash
  • Photosensitivity

• Parents

  • Collagen vascular disease

• Treatments

  • Methotrexate
  • Azathioprine
  • Intravenous immunoglobulin
  • Glucocorticoid

• Description

  • "Onset weeks to months Associated with internal malignancy in 40% of cases over 60"