Cushing syndrome

external

• Synonyms

  • Cushingoid facies

• Causes

  • Corticosteroid
  • Ectopic adrenocorticotrophic hormone secretion
  • Adrenal cortical hyperfunction
  • Adrenocorticotrophic hormone-secreting pituitary adenoma
  • Pseudocushings
  • Polyostotic fibrous dysplasia

• Effects

  • Moon face
  • Atrophic skin
  • Hirsutism
  • Obesity
  • Supraclavicular fat pad
  • Centripetal fat distribution
  • Carpal tunnel syndrome
  • Abdominal striae
  • Fragile blood vessel
  • Hyperglycaemia
  • Impaired glucose tolerance
  • Osteoporosis
  • Proximal myopathy
  • Peptic ulcer
  • Depression
  • Endocrine fluid retention
  • Immunosuppression
  • Acanthosis nigricans
  • Benign intracranial hypertension
  • Hypokalaemia
  • Hypertriglyceridaemia
  • Hypercholesterolaemia
  • Acquired cataract
  • Chemosis
  • Metabolic alkalosis
  • Plethoric face

• Parents

  • Endocrine disease

• Treatments

  • Cabergoline
  • Adrenalectomy
  • Hypophysectomy

• Description

  • "high cortisol Managment 1)Medication associated Cushings: -stop medication -needs gradual tapering 2)Adrenal associated Cushings -Adenoma - Remove adenoma -Hyperplasia - bilateral adrenalectomy -Cabergoline 3)Pitutiary associated cushings -Subtotal hypophysectomy OR -Radiotherapy"