Cranio-cleido dysostosis

external

• Synonyms

  • Craniocleidal dysostosis
  • Cleidocranial dysostosis
  • Mutational dysostosis

• Causes

  • RUNX2 gene mutation

• Effects

  • Fontanelle closure delayed
  • Cranial sutures widened
  • Frontal bossing
  • Supernumerary teeth
  • Prognathism
  • Hypoplastic clavicle
  • Hypoplastic iliac bones
  • Wide pubic symphysis
  • Coxa vara

• Parents

  • Congenital skeletal dysplasia
  • Autosomal dominant disorder

• Description

  • "Delayed ossification of midline structures."