Chronic lymphocytic leukaemia

external

• Synonyms

  • CLL
  • Chronic lymphatic leukaemia

• Causes

  • Philadelphia chromosome

• Effects

  • Lymphocytosis
  • Antiplatelet antibody
  • Warm antibody haemolysis7.0%
  • Prolymphocytic transformation
  • Richter syndrome
  • Smear cells
  • Hypophosphataemia
  • Defective B-cell function

• Parents

  • Lymphoid leukaemia
  • Lymphoproliferative disorder

• Children

  • Chronic B-cell leukaemia
  • Chronic T-cell leukaemia

• Treatments

  • Chlorambucil
  • Radiotherapy

• Description

  • "99% CD5 positive B-cells >60-year old male 25% asymptomatic 7% develop haemolysis Initially does not require treatment."