Chronic liver disease

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• Synonyms

  • Parenchymal liver disease
  • Chronic hepatic disease

• Causes

  • Alcoholic liver disease
  • Hepatitis B
  • Hepatitis C
  • Non alcoholic fatty liver disease
  • Biliary cirrhosis
  • Haemochromatosis
  • Systemic venous congestion
  • Chronic active hepatitis
  • Liver metastasis
  • Wilson's disease
  • Alpha-1 antitrypsin deficiency
  • Budd-Chiari syndrome
  • Fasciola hepatica
  • Schistosomiasis
  • Alpers syndrome

• Effects

  • Cirrhosis
  • Portal hypertension
  • Hepatocellular jaundice
  • Hepatomegaly
  • Elevated liver enzymes
  • Hypoalbuminaemia
  • High oestrogen
  • Bleeding disorder
  • Liver failure
  • Spider naevi
  • Palmar erythema
  • Telangiectasia
  • Fingernail clubbing
  • Secondary hyperlipidaemia
  • Weight loss
  • Muscle wasting
  • Metabolic neuropathy
  • Osteoporosis
  • Osteomalacia
  • Lag storage curve
  • Macrocytosis

• Parents

  • Liver disease