"Trophoblastic cancer of the placenta
50% develop on a hydatiform mole
20% with prevoius ectopic /spontaneous abortion
Prognosis
At diagnosis 90% have lung metastases!
With chemotherapy- 80% 5-year survival.
Prognosis poor with liver and brain metastases
Choriocarcinoma also occur de novo in the testicle & ovary"