Carcinoma of pancreas

external

• Synonyms

  • Pancreatic cancer
  • Ca pancreas

• Causes

  • Cigarette smoking
  • Diabetes mellitus
  • Obesity
  • Chronic pancreatitis
  • Peutz-Jegher syndrome
  • Polygenic inheritance
  • BRCA2 gene mutation

• Effects

  • Thrombophlebitis migrans
  • Neoplastic coagulation factors
  • Livedo reticularis
  • Inappropriate ADH secretion
  • Panniculitis
  • Monospot test positive
  • Homocysteinaemia
  • Cancers with polygenic inheritance

• Parents

  • Gastrointestinal pathology
  • Intra-abdominal malignancy

• Children

  • Carcinoma Head of Pancreas75.0%
  • Carcinoma Body of Pancreas20.0%
  • Carcinoma Tail of Pancreas0.0%

• Treatments

  • Whipple's operation
  • Gemcitabine
  • 5-fluorouracil
  • Weight loss

• Description

  • " Operable in only 20% 5yr survival after resection = 20%"