Bone marrow suppression

external

• Synonyms

  • Myelosuppression

• Causes

  • Bone marrow infiltration
  • Immunological bone marrow destruction
  • Pernicious anaemia
  • Cytotoxic drug
  • Phenytoin
  • Azathioprine
  • Mycophenolate mofetil
  • Allopurinol
  • Sulphonamide
  • Osteopetrosis

• Effects

  • Pancytopaenia
  • Ineffective granulopoiesis
  • Myelophthisic anaemia
  • Decreased platelet production
  • Immunosuppression