Birt-Hogg-Dube Syndrome

external

• Synonyms

  • Fibrofolliculomas

• Causes

  • FLCN gene mutation

• Effects

  • Fibrofolliculoma
  • Chromophobe renal cell carcinoma30.0%
  • Lung cyst80.0%

• Parents

  • Congenital neoplastic syndrome
  • Autosomal dominant disorder

• Description

  • "Fibrofolliculomas are always around the nose and ear. 7 times greater renal cancer risk than the unaffected population. These are not renal cell carcinomas however."