Antiphospholipid syndrome

external

• Synonyms

  • APLS

• Causes

  • Anti-cardiolipin antibody
  • Lupus anticoagulant
  • Rheumatoid disease
  • Diffuse systemic sclerosis
  • Systemic lupus erythematosus
  • Temporal arteritis
  • Sjogren syndrome
  • Behcet disease
  • Psoriatic arthropathy
  • Human immunodeficiency virus
  • Hepatitis C
  • Quaternary syphilis
  • Multiple sclerosis
  • Acquired immunodeficiency syndrome

• Effects

  • Antiplatelet antibody
  • Recurrent miscarriage
  • Raynaud phenomenon
  • Positive VDRL
  • Chorea
  • Livedo reticularis
  • Transient ischaemic attack
  • Migraine
  • Avascular necrosis
  • Acquired hypercoagulable state
  • Secondary pulmonary hypertension
  • Secondary vasculitis

• Parents

  • Haematological autoimmune disease

• Description

  • "25% have thrombocytopenia"