Acute promyelocytic leukaemia

external

• Synonyms

  • Acute myeloid leukaemia M3
  • AML-M3
  • APL
  • AML 3

• Effects

  • Disseminated intravascular coagulation
  • Bilobed mononucleocyte
  • Promyelocyte

• Parents

  • Acute myeloid leukaemia

• Description

  • "Accounts for 15% of AML Cure rate 70% if remission is achieved Associated with t(15:17)q
  • causing retinoic acid receptor fusion gene Rx All-trans retinoic acid"