Acanthosis nigricans

external

• Causes

  • Obesity
  • Type II diabetes mellitus
  • Cushing syndrome
  • Acromegaly
  • Polycystic ovary syndrome
  • Gastric adenocarcinoma
  • Colorectal carcinoma
  • Lymphoma
  • High oestrogen

• Effects

  • Tripe palm

• Parents

  • Congenital skin disease
  • Autosomal dominant disorder
  • Skin signs on observation
  • Endocrine skin disorder

• Description

  • "Velvety hyperpigmentation of neck
  • axilla
  • groin TYPES: -Hereditary -Endocrinal: Increased circulating insulin- activates keratinocyte -Paraneoplastic syndrome."